RT Journal Article
T1 Bidirectional Hiyama-Denmark cros-coupling reactions of bissilyldeca-1,3,5,7,9-pentaenes for the synthesis of symmetrical and non-symmetrical carotenoids
A1 Rivas Landín, Áurea
A1 Pérez Revenga, Víctor
A1 Álvarez Rodríguez, Maria Rosana
A1 Rodríguez de Lera, Ángel
K1 2306 Química Orgánica
AB The construction of the carotenoid skeleton by Pd‐catalyzed Csp2−Csp2 cross‐coupling reactions of symmetrical and non‐symmetrical 1,10‐bissilyldeca‐1,3,5,7,9‐pentaenes and the corresponding complementary alkenyl iodides has been developed. Reaction conditions for these bidirectional and orthogonal Hiyama–Denmark cross‐coupling reactions of bisfunctionalized pentaenes are mild and the carotenoid products preserve the stereochemical information of the corresponding oligoene partners. The carotenoids synthesized in this manner include β,β‐carotene and (3R,3′R)‐zeaxanthin (symmetrical) as well as 9‐cis‐β,β‐carotene, 7,8‐dihydro‐β,β‐carotene and β‐cryptoxanthin (non‐symmetrical).
PB Chemistry - A European Journal
SN 09476539
YR 2019
FD 2019-11-13
LK http://hdl.handle.net/11093/8040
UL http://hdl.handle.net/11093/8040
LA eng
NO Chemistry - A European Journal, 25(63): 14399-14407 (2019)
NO Agencia Estatal de Investigación | Ref. SAF2016-77620-R
DS Investigo
RD 26-mar-2025