RT Journal Article T1 Calcium phosphate grafts produced by rapid prototyping based on laser cladding A1 Comesaña Piñeiro, Rafael A1 Lusquiños Rodríguez, Fernando A1 Del Val Garcia, Jesús A1 Malot, T A1 López Álvarez, Miriam A1 Riveiro Rodríguez, Antonio A1 Quintero Martínez, Félix A1 Boutinguiza Larosi, Mohamed A1 Aubry, P A1 De Carlos Villamarin, Alejandro Leonides A1 Pou Saracho, Juan María K1 3312 Tecnología de Materiales K1 3303 Ingeniería y Tecnología Químicas AB Rapid prototyping based on laser cladding by powder injection has been used to produce calcium phosphate three-dimensional grafts without using molds. Precursor material comprising of hydroxyapatite (HA) powder was irradiated by means of an infrared Nd:YAG laser. The processing parameters and the thermal history of the processed material have been assessed and the process has been optimized to obtain solid parts. Processing by laser cladding lead to complete dehydroxylation of the precursor HA, the obtained microstructure is composed by an alpha-tricalcium phosphate ( -TCP) matrix with nucleated tetracalcium phosphate (TTCP) grains, in coexistence with oxyapatite and amorphous calcium phosphate. The produced bioceramic grafts were observed to be bioactive, leading to calcium-deficient hydroxyapatite precipitation and promoting pre-osteoblastic cell attachment and proliferation during “in vitro” cell culture test. PB Journal of the European Ceramic Society SN 09552219 YR 2011 FD 2011-01 LK http://hdl.handle.net/11093/6937 UL http://hdl.handle.net/11093/6937 LA eng NO Journal of the European Ceramic Society, 31(1-2): 29-41 (2011) NO Ministerio de Ciencia e Innovación | Ref. MAT2006-10481 DS Investigo RD 13-dic-2024