RT Journal Article
T1 Three-dimensional bioactive glass implants fabricated by rapid prototyping based on CO2 laser cladding
A1 Comesaña Piñeiro, Rafael
A1 Lusquiños Rodríguez, Fernando
A1 Del Val Garcia, Jesús
A1 López Álvarez, Miriam
A1 Quintero Martínez, Félix
A1 Riveiro Rodríguez, Antonio
A1 Boutinguiza Larosi, Mohamed
A1 De Carlos Villamarin, Alejandro Leonides
A1 Jones, Julian Raymond
A1 Hill, Robert G
A1 Pou Saracho, Juan María
K1 3312 Tecnología de Materiales
K1 3303 Ingeniería y Tecnología Químicas
AB Three-dimensional bioactive glass implants were produced by rapid prototyping based on laser cladding without using moulds. CO2 laser radiation was employed to melt 45S5 and S520 bioactive glass particles and to deposit the material layer by layer following a desired geometry. Controlled thermal input and cooling rate by fine tuning of the processing parameters allowed the production of crack-free fully dense implants. Microstructural characterization revealed chemical composition stability, but crystallization during processing was extensive when 45S5 bioactive glass was used. Improved results were obtained using the S520 bioactive glass, which showed limited surface crystallization due to an expanded sintering window (the difference between the glass transition temperature and crystallization onset temperature). Ion release from the S520 implants in Tris buffer was similar to that of amorphous 45S5 bioactive glass prepared by casting in graphite moulds. Laser processed S520 scaffolds were not cytotoxic in vitro when osteoblast-like MC3T3-E1 cells were cultured with the dissolution products of the glasses; and the MC3T3-E1 cells attached and spread well when cultured on the surface of the materials.
PB Acta Biomaterialia
SN 17427061
YR 2011
FD 2011-09
LK http://hdl.handle.net/11093/6936
UL http://hdl.handle.net/11093/6936
LA eng
NO Acta Biomaterialia, 7(9): 3476-3487 (2011)
NO Ministerio de Educación y Ciencia | Ref. MAT2006-10481
DS Investigo
RD 10-dic-2024