RT Journal Article T1 Survey of Crimean-Congo hemorrhagic fever enzootic focus, Spain, 2011–2015 A1 Negredo, Ana A1 Habela, Miguel Ángel A1 Ramírez de Arellano, Eva A1 Diez, Francisco A1 Lasala, Fátima A1 López, Pablo A1 Sarriá, Ana A1 Labiod, Nuria A1 Calero Bernal, Rafael A1 Arenas Busto, Miguel A1 Tenorio, Antonio A1 Estrada Peña, Agustín A1 Sánchez Seco, Maria Paz K1 2409 Genética K1 2420 Virología AB During 2011–2015, we conducted a Crimean-Congo hemorrhagic fever virus (CCHFV) survey in captured ticks that were feeding mainly on wild and domestic ungulates in Spain, where presence of this virus had been reported previously. We detected CCHFV RNA in Hyalomma lusitanicum and H. marginatum ticks for 3 of the 5 years. The rate of infected ticks was 2.78% (44/1,579), which was similar to those for other countries in Europe with endemic foci for CCHFV (Kosovo, Bulgaria, and Albania). These data confirm the established spread of CCHFV into western Europe. Phylogenetic study of the small RNA segment showed Africa-3 clade as the only genotype identified, although we observed cocirculation of genetic variants during 2011 and 2015. We could not rule out genetic reassortments because of lack of sequence data for the medium and large RNA segments of the virus genome. PB Emerging Infectious Diseases SN 10806040 YR 2019 FD 2019-06 LK http://hdl.handle.net/11093/6516 UL http://hdl.handle.net/11093/6516 LA eng NO Emerging Infectious Diseases, 25(6): 1177-1184 (2019) NO Ministerio de Economía y Competitividad | Ref. RD12/0018/0006 DS Investigo RD 27-mar-2025