RT Journal Article
T1 Metabolic and genetic derangement: a review of mechanisms involved in arsenic and lead toxicity and genotoxicity
A1 Sadiku, Olubusayo Olujimi
A1 Rodríguez Seijo, Andrés
K1 2403 Bioquímica
K1 2303.17 Compuestos de Plomo
K1 2490 Neurociencias
AB Urbanisation and industrialisation are on the rise all over the world. Environmental contaminants such as potentially toxic elements (PTEs) are directly linked with both phenomena. Two PTEs that raise greatest concern are arsenic (As) and lead (Pb) as soil and drinking water contaminants, whether they are naturally occurring or the consequence of human activities. Both elements are potential carcinogens. This paper reviews the mechanisms by which As and Pb impair metabolic processes and cause genetic damage in humans. Despite efforts to ban or limit their use, due to high persistence both continue to pose a risk to human health, which justifies the need for further toxicological research.
PB Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology
SN 18486312
YR 2022
FD 2022-12
LK http://hdl.handle.net/11093/6455
UL http://hdl.handle.net/11093/6455
LA eng
NO Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology, 73(4): 244-255 (2022)
NO Agencia Estatal de Investigación | Ref. IJC2020-044197-I
DS Investigo
RD 13-dic-2024