RT Journal Article T1 Microwave-assisted autohydrolysis of avocado seed for the recovery of antioxidant phenolics and glucose A1 Del Castillo Llamosas, Alexandra A1 Eibes, Gemma A1 Ferreira Santos, Pedro Miguel A1 Perez Perez, Alba A1 Garcia Del Rio, Pablo A1 Gullon Estevez, Beatriz K1 3303.03 Procesos Químicos K1 3303.04 Separación Química K1 2304.19 Polisacáridos AB This study describes the valorization of avocado seed (AS) within a green biorefinery concept using microwave-assisted autohydrolysis. After the treatment at temperatures of 150–230 ◦C for 5 min, the resulting solid and liquor were characterized. The temperature of 220 ◦C led to the simultaneous optimal values of antioxidant phenolics/flavonoids (42.15 mg GAE/g AS, 31.89 RE/g AS, respectively) and glucose + glucooligosaccharides (38.82 g/L) in the liquor. Extraction with ethyl acetate allowed the recovery of the bioactive compounds while maintaining the polysaccharides in the liquor. The extract was rich in vanillin (99.02 mg/g AS) and contained several phenolic acids and flavonoids. The solid phase and the phenolic-free liquor were subjected to enzymatic hydrolysis to produce glucose, reaching values of 9.93 and 105 g glucose/L, respectively. This work demonstrates that microwave-assisted autohydrolysis is a promising technology to obtain fermentable sugars and antioxidant phenolic compounds from avocado seeds following a biorefinery scheme. PB Bioresource Technology SN 09608524 YR 2023 FD 2023-10 LK http://hdl.handle.net/11093/5011 UL http://hdl.handle.net/11093/5011 LA eng NO Bioresource Technology, 385, 129432 (2023) NO Universidade de Vigo/CISUG DS Investigo RD 13-ene-2025