RT Journal Article T1 Negative samples for improving object detection—A case study in aI-assisted colonoscopy for polyp detection A1 Nogueira Rodríguez, Alba A1 González Peña, Daniel A1 Reboiro Jato, Miguel A1 López Fernández, Hugo K1 3207.03 Carcinogénesis K1 3210 Medicina Preventiva K1 1203.20 Sistemas de Control Médico AB Deep learning object-detection models are being successfully applied to develop computer-aided diagnosis systems for aiding polyp detection during colonoscopies. Here, we evidence the need to include negative samples for both (i) reducing false positives during the polyp-finding phase, by including images with artifacts that may confuse the detection models (e.g., medical instruments, water jets, feces, blood, excessive proximity of the camera to the colon wall, blurred images, etc.) that are usually not included in model development datasets, and (ii) correctly estimating a more realistic performance of the models. By retraining our previously developed YOLOv3-based detection model with a dataset that includes 15% of additional not-polyp images with a variety of artifacts, we were able to generally improve its F1 performance in our internal test datasets (from an average F1 of 0.869 to 0.893), which now include such type of images, as well as in four public datasets that include not-polyp images (from an average F1 of 0.695 to 0.722). PB Diagnostics SN 20754418 YR 2023 FD 2023-03-03 LK http://hdl.handle.net/11093/4679 UL http://hdl.handle.net/11093/4679 LA eng NO Diagnostics, 13(5): 966 (2023) NO Ministerio de Ciencia y Competitividad y Ministerio de Ciencia e Innovación | Ref. DPI2017-87494-R DS Investigo RD 24-ene-2025