RT Journal Article T1 Bioactive compounds of Verbascum sinuatum L.: health benefits and potential as new ingredients for industrial applications A1 Donn, Pauline A1 Barciela, Paula A1 Pérez Vázquez, Ana A1 Cassani, Lucía A1 Simal Gándara, Jesús A1 Prieto Lage, Miguel Ángel K1 3309 Tecnología de Los Alimentos K1 3209 Farmacología K1 2302 Bioquímica AB Verbascum sinuatum (V. sinuatum) is a plant belonging to the Scrophulariaceae family that has been used as an ingredient in traditional medicine infusions for the treatment of many diseases. The aerial part of this plant is a source of bioactive compounds, especially polyphenols and iridoids. Moreover, antioxidant activity studies have shown that V. sinuatum phenolic and flavonoid composition is higher than those in other plants of the same genus. V. sinuatum bioactive compound composition could vary according to the harvesting location, growing conditions of the plants, sample preparation methods, type and concentration of the extraction solvent, and the extraction methods. The obtention of these compounds can be achieved by different extraction techniques, most commonly, maceration, heat assisted extraction, and infusion. Nevertheless, since conventional extraction techniques have several drawbacks such as long times of extraction or use of large amounts of solvents, the use of green extraction techniques is suggested, without affecting the efficiency of the extraction. Moreover, V. sinuatum bioactive compounds have several biological activities, such as antioxidant, anticancer, cardiovascular, antimicrobial, antidiabetic, and neuroprotective activities, that may be increased by encapsulation. Since the bioactive compounds extracted from V. sinuatum present good potential as functional food ingredients and in the development of drugs or cosmetics, this review gives an approach of the possible incorporation of these compounds in the food and pharmacological industries. PB Biomolecules SN 2218273X YR 2023 FD 2023-02-24 LK http://hdl.handle.net/11093/4673 UL http://hdl.handle.net/11093/4673 LA eng NO Biomolecules, 13(3): 427 (2023) NO MICINN | Ref. RYC-2017-22891 DS Investigo RD 13-dic-2024