RT Journal Article
T1 Palladium nanoparticles synthesized by laser ablation in liquids for antimicrobial applications
A1 Fernández Arias, Mónica
A1 Vilas, Ana María
A1 Boutinguiza Larosi, Mohamed
A1 Rodríguez, Daniel
A1 Arias González, Felipe
A1 Pou Álvarez, Pablo
A1 Riveiro Rodríguez, Antonio
A1 Gil, Javier
A1 Pou Saracho, Juan María
K1 2209.10 láseres
K1 2302 Bioquímica
K1 3310 Tecnología Industrial
AB Antibiotic resistance is a leading cause of death worldwide. In this paper, we explore new alternatives in the treatment of infections. Noble metal nanoparticles could help to mitigate this problem. In this work, palladium nanoparticles were synthesized by laser ablation in order to explore their antimicrobial capacity. To obtain palladium nanoparticles, a palladium plate immersed in water, or methanol, was ablated, using two pulsed lasers that emit radiation with wavelengths of 532 nm and 1064 nm, respectively. Pure Pd-NPs with crystalline microstructure and rounded shape were obtained. The nanoparticles’ size is more homogeneous if the laser wavelength is 532 nm, and it decreases when methanol is used as solvent, reaching mean diameters smaller than 6 nm. With the objective of studying antimicrobial activity against Staphylococcus aureus, the Pd-NPs were immobilized on the surface of titanium discs. The release of palladium ions was recorded during the first seven days, and the cytotoxicity of the immobilized NPs was also tested with L929 mouse fibroblast cell line. Palladium nanoparticles synthesized by means of the infrared laser in methanol showed a strong inhibitory effect on S. aureus and good cytocompatibility, with no toxic effect on fibroblast cells.
PB Nanomaterials
SN 20794991
YR 2022
FD 2022-07-29
LK http://hdl.handle.net/11093/3802
UL http://hdl.handle.net/11093/3802
LA eng
NO Nanomaterials, 12(15): 2621 (2022)
NO Xunta de Galicia | Ref. ED431C 2019/23
DS Investigo
RD 25-ene-2025