RT Journal Article T1 Health promoting properties of bee royal jelly: food of the queens A1 Collazo, Nicolas A1 Carpena Rodríguez, María A1 Núñez Estévez, Bernabé A1 Otero, Paz A1 Simal Gándara, Jesús A1 Prieto Lage, Miguel Angel K1 3104.01 Apicultura K1 3309.20 Propiedades de Los Alimentos K1 3206 Ciencias de la Nutrición AB Royal jelly (RJ) demand is growing every year and so is the market for functional foods in general. RJ is formed by different substances, mainly carbohydrates, proteins, and lipids, but also vitamins, minerals, and phenolic or volatile compounds in lower proportion. Major royal jelly proteins (MRJP) are, together with 10-hydroxy-2-decenoic acid (10-HDA), key substances of RJ due to their different biological properties. In particular, 10-HDA is a unique substance in this product. RJ has been historically employed as health enhancer and is still very relevant in China due to the traditional medicine and the apitherapy. Nowadays, it is mainly consumed as a functional food or is found in supplements and other formulations for its health-beneficial properties. Within these properites, anti-lipidemic, antioxidant, antiproliferative, antimicrobial, neuroprotective, anti-inflammatory, immunomodulatory, antiaging, and estrogenic activities have been reported for RJ or its specific components. This manuscript is aimed at reviewing the current knowledge on RJ components, their assessment in terms of authenticity, their biological activities, and related health applications. PB Nutrients SN 20726643 YR 2021 FD 2021-02-07 LK http://hdl.handle.net/11093/1954 UL http://hdl.handle.net/11093/1954 LA eng NO Nutrients, 13(2): 543 (2021) NO European Commission | Ref. 0377_IBERPHENOL_6_E DS Investigo RD 13-dic-2024