The effect of clarithromycin toxicity on the growth of bacterial communities in agricultural soils

Abstract

The presence of antibiotics in different environmental matrices is a growing concern. The introduction of antibiotics into the soil is mainly due to sewage treatment plants. Once in the soil, antibiotics may become toxic to microbial communities and, as a consequence, can pose a risk to the environment and human health. This study evaluates the potential toxicity of the antibiotic clarithromycin (CLA) in relation to the bacterial community of 12 soils with different characteristics. Bacterial community growth was evaluated in soils spiked in the laboratory with different concentrations of CLA after 1, 8, and 42 incubation days. The results indicated that the addition of clarithromycin to the soil may cause toxicity in the bacterial communities of the soil. In addition, it was observed that toxicity decreases between 1 and 8 incubation days, while the bacterial community recovers completely in most soils after 42 incubation days. The results also show that soil pH and effective cation exchange capacity may influence CLA toxicity.